Research Technician – LMS 933

Gut Signalling and Metabolism

(Maternity cover, 6 months with possibility of extension)

£27,077 – £30,852 pa inclusive

London, UK

Applications are invited for a research technician position in the Gut Signalling and Metabolism group at the MRC Laboratory of Medical Sciences (LMS) at the Hammersmith Hospital campus of Imperial College London.  We are looking for an enthusiastic and curious individual with excellent organisational skills and a high attention to detail.

The group is led by Professor Irene Miguel-Aliaga and investigates how the gut and its neurons communicate with each other to maintain or perturb homeostasis (Linneweber 2014 Cell, Cognigni 2011 Cell Metab). Our recent work has shown that the digestive system of males and females is different, and that these differences can affect whole-body physiology – from reproductive output to susceptibility to tumorigenic insults (Hudry 2016 Nature, Reiff 2015 eLife). Our ongoing work is exploring these differences further in various directions, with the overarching goal of understanding how adaptable and diverse adult organs can be and why. To this end, we make use of several model systems, such as mouse and intestinal organoids (Perea 2017 EMBO J). We also use a variety of experimental approaches including genetics, transcriptomics, metabolomics and imaging, as well as a range of physiological and behavioural assays for phenotyping.

We are located in a modern building with core facilities, and belong to the vibrant and scientifically outstanding LMS, affiliated with Imperial College London. The lab provides an environment that values and support diversity, and remains committed to internationalism.

Applicants should have a Bachelor’s degree in a relevant biological subject, and experience in laboratory-based research, including some practical experience with mouse/mammalian cell culture techniques.

This post is only open to UK/EU residents, as MRC cannot apply for a Certificate of Sponsorship for this post under Tier 2 of the UK Border Agency’s Points Based System.