About me:
I moved to the LMS after completing a PhD and postdoc at the University of Oxford and University of Queensland. In my previous roles I was working on motor neuron disease, specifically characterising genomically humanised mouse models of FUS-ALS. I am particularly interested in the role of muscle in health and disease and so I joined the LMS to study the role of AMPK activation in skeletal muscle. I will be using a combination of in vitro and in vivo models to study the effect of AMPK- γ3 activation in muscle metabolism and physiology to try and understand how this could be targeted to reduce or prevent muscle wasting.
The cellular stress group was formed in 1992, and the team led by David Carling aims to understand the physiological role of the AMP-activated protein kinase cascade in metabolism.