About me:
At the LMS, I study how enhancer–promoter interactions shape gene regulation in the Functional Gene Control group. Born and raised in Taiwan, I moved to the University of Illinois at Urbana-Champaign for my PhD, where I uncovered new functions of KRAB zinc finger proteins. My first postdoctoral position took me to Paris, where I developed Nano-C, a method combining Chromosome Conformation Capture and Nanopore sequencing to reveal complex chromatin interactions. In 2022, I joined the University of Oxford, where I developed methods to detect CRISPR-mediated off-target effects and structural alterations. Across these experiences, I have created tools to make genome editing safer and more precise, while deepening our understanding of how the genome is organized and regulated.
The functional gene control group headed by Mikhail Spivakov investigates the logic of gene regulation using a combination of experimental and computational approaches.