£41,344 plus London allowances £5,385 per annum*
POSTDOCTORAL POSITIONS IN DEVELOPMENTAL EPIGENETICS
Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics. Join leading labs exploring germline demethylation, gene regulation, or genome architecture across diverse developmental and disease contexts.
Applicants are encouraged to review all five posts and clearly state in their cover letter the position(s) that align with their interests and expertise (see “How to Apply” below):
Join the Reprogramming and Chromatin Laboratory (Hajkova) to uncover how epigenetic landscapes are reset in the context of the germline cycle. We investigate the molecular mechanisms that drive large-scale chromatin reorganisation and DNA modification dynamics during developmental epigenetic reprogramming, the molecular triggers and the functional consequences of these naturally occurring processes. Our work combines in vivo and in vitro developmental models with cutting-edge genomic, proteomic, embryo manipulation and imaging technologies to explore how epigenetic information is erased, rewritten, and interpreted. By revealing the principles of epigenetic plasticity, we aim to understand how developmental potential is regulated and how its disruption may contribute to disease.
Development & Transcriptional Control
Join the Development & Transcriptional Control Laboratory (Metzis) to decipher one of developmental biology’s most fundamental questions: how the correct cell types form in the right place and proportion during embryogenesis. We combine mouse genetics, stem cell-based models, and genome engineering to investigate how cells control their identity. These systems support quantitative and mechanistic studies, allowing us to address questions across scales: from the function of cis-regulatory elements, to the morphogenesis of the body plan. We welcome applicants eager to join and contribute to a collaborative and multidisciplinary team. Help us develop new tools and methodologies to decode the regulatory logic of mammalian development.
Join the Developmental Epigenomics Laboratory (Vaquerizas) to investigate how genome architecture and epigenetic regulation shape cell identity and function. We apply advanced single-cell and spatial multiomics technologies to address fundamental questions in gene regulation, development, and disease. Our multidisciplinary team integrates molecular biology, computational biology, and systems-level approaches to study processes such as 3D genome organisation, epitranscriptomics, and gene regulatory networks. We welcome creative scientists excited to contribute to a collaborative and supportive research environment, and to help drive innovation in decoding the regulatory logic of cellular function, development, and disease.
What we offer
As well as the exciting opportunities these roles present, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more – Benefits
How to apply
For full details of these posts and to complete an online application, visit:
MRC Postdoctoral Research Scientist LMS 2662 – Medical Research Council
MRC Postdoctoral Research Scientist LMS 2663 – Medical Research Council
MRC Postdoctoral Research Scientist (Mixed Wet/Dry Laboratory) LMS 2665 – Medical Research Council
MRC Postdoctoral Research Scientist/Lab Manager LMS 2666 – Medical Research Council
and upload your CV, names and contacts of two scientific references along with a cover letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be accepted. Please quote reference number of the post you are applying.
Closing date: 12 August
The final appointment will be subject to pre-employment screening
*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two.
Please note that applications may be reviewed by both LMS and Imperial staff
Athena SWAN
In 2017, the Institute received an Athena SWAN Silver Award to recognize its commitment to advancing women’s careers in science and research.
At the LMS there are three working groups which deliver on the action plan developed for the silver application.
Equality, diversity and wellbeing
The MRC LMS is committed to creating equality of opportunity to all members of the organisation, regardless of their background, and promoting diversity and inclusivity. We observe the Medical Research Council’s Equality and Diversity Vision, which sets out the MRC’s commitment to fulfill its obligations as a public body under the Equality Act 2010.
Technician’s Commitment
The LMS is a signatory to the Technician Commitment, a sector-wide initiative led by the Science Council and the Gatsby Foundation which aims to address the particular career challenges faced by technical and scientific support staff.
We provide opportunities to work alongside some of the top medical researchers on the planet, from our state-of-the-art research facilities.