About me
Experience:
Fellow of the Academy of Medical Sciences (FMedSci)
2009 -
Present
Programme Leader (MRC LMS)
2009 -
Present
Professor of Diabetes and Endocrinology (Imperial College London)
2005 -
Fellow of the Royal College of Physicians (FRCP)
2004 -
2009
Professor (University College London)
2000 -
2004
MRC Senior Clinical Fellowship (Imperial College London)
2002 -
2000 -
1996 -
2000
1996 -
1994 -
1993 -
1996
1990 -
1987 -
1984 -
Research focus:
My areas of focus are based on my interest in the fundamental role that molecular signalling pathways play in the regulation of mammalian physiology. My work focusses on the signals and cells that control feeding and metabolism with a view to both understanding the causes of diabetes and obesity and to developing therapeutic approaches to these conditions. These signalling mechanisms have also been shown to regulate ageing and healthspan and so this is another important area for my research.
Joined LMS:
2009
About me:
I joined LMS because it was an ideal environment for me to undertake the complex multi-disciplinary programme that forms the core of my research. The combination of excellent colleagues and excellent infrastructure were key. The close proximity to the clinical environment was also a very important factor for my practice as a physician.
My awards and achievements:
Linacre Fellowship and Medal
Royal College of Physicians of London, 2001
Fellowship of the Academy of Medical Sciences 2011
Impact of my work:
Our work has played a key role in advancing our understanding of the mechanisms that control food intake and various aspects of metabolism including how the hormone insulin is both produced and how it works to control blood sugar levels. We have also identified key signalling pathways that control lifespan and these are beginning to be targeted as potential treatments for the diseases of ageing in humans.