The Bioinformatics facility supports small and large-scale computational biology projects across the LMS.
Working in close partnership with the research groups, the facility provides analysis services for scientists and support for those undertaking their own projects.
Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P. Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742. doi: 10.1038/s41586-021-04208-5. Epub 2021 Dec 8. PMID: 34880491.
Karimi MM, Guo Y, Cui X, Pallikonda HA, Horková V, Wang YF, Gil SR, Rodriguez-Esteban G, Robles-Rebollo I, Bruno L, Georgieva R, Patel B, Elliott J, Dore MH, Dauphars D, Krangel MS, Lenhard B, Heyn H, Fisher AG, Štěpánek O, Merkenschlager M. The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus. Nat Commun. 2021 Jan 4;12(1):99. doi: 10.1038/s41467-020-20306-w. PMID: 33397934; PMCID: PMC7782583.
Weiss FD, Calderon L, Wang YF, Georgieva R, Guo Y, Cvetesic N, Kaur M, Dharmalingam G, Krantz ID, Lenhard B, Fisher AG, Merkenschlager M. Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin. Nat Commun. 2021 May 18;12(1):2919. doi: 10.1038/s41467-021-23141-9. PMID: 34006846.
Hudry B, Khadayate S, Miguel-Aliaga I. The sexual identity of adult intestinal stem cells controls organ size and plasticity. Nature. 2016 Feb 18;530(7590):344-8. doi: 10.1038/nature16953. PMID: 26887495; PMCID: PMC4800002.
