My Research

Steroids and metabolism

The Arlt lab, which focusses on the role of steroid metabolism and action in human disease, moved to the LMS in 2023. Our work explores tissue-specific regulation of steroid action with a focus on the role of androgens in metabolic dysfunction. We are very interested in mechanisms that explain sex differences in the impact of androgens on metabolism.

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Selected publications

Martin J Whitaker, Miguel Debono and Richard J Ross “Developing oral chronotherapy for cortisol replacement in congenital adrenal hyperplasia” Clinical Endocrinology (2023)

Miguel Debono, Charlotte J Elder, Jen Lewis, Jane Fearnside, Sharon Caunt, Simon Dixon, Richard M. Jacques, John Newell-Price, Martin J Whitaker, Brian Keevil, Richard J. Ross. “Home Waking Salivary Cortisone to Screen for Adrenal Insufficiency” New England Journal of Medicine: Evidence (2023)