MRC Investigator Scientist in Bioinformatics & Genetics

Computational Cardiac Imaging Group

(3 Years fixed term)

Salary: £41,843 – £43,962 plus London allowances (£3,913 & £1,472) per annum

London, UK

The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus. For more information, visit oreganlab.org.

The Computational Cardiac Imaging Group works at the intersection of clinical imaging, bioinformatics, computer vision and molecular cardiology to explore the mechanisms underlying heart function. The group uses machine learning to analyse cardiac motion for predicting patient outcomes, discovering potential therapeutic targets and identifying genetic risk factors. We use a flexible and inter-disciplinary approach to research that moves between individuals, populations and model organisms.

Applicants should have substantial research experience in machine learning, statistics and bioinformatics and will develop models for biological age prediction from multiple image derived phenotypes. Expert knowledge of a wide range of statistical tools including gradient boosting algorithms, as well as causal inference techniques such as structural equation modelling is required. The candidate should have proven programming experience including Python and R. Previous work on biomedical datasets and genomics would be an advantage including performing GWAS and rare variant analyses in biobanked populations. We are also looking for an ability to innovate and adapt techniques from other domains.

The post offers an exciting opportunity to work at the cutting-edge of translational medicine research in a vibrant and supportive multi-disciplinary team that crosses traditional scientific domains. The post holder will have the opportunity to liaise with an extensive network of collaborators, attend scientific conferences, and publish the results of their work in leading journals. There is also a vibrant and supportive community at the LMS with outstanding opportunities for career development and training.

 

 

The MRC is an equal opportunities employer.

‘Leading Science for Better Health’

Final appointment will be subject to pre-employment screening

 

Please Note: Ahead of the launch of the new LMS website, planned for 18^th November we will need to have two short periods of “outage” for our website in order to facilitate the changeover, one planned on Wednesday 13^th Nov (1100-1300), and one on the launch day, 18^th Nov of maximum 2 hours (1000-1200).

During this time anyone trying to reach the website will receive an error message saying the website is unreachable.